4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde → 4-Pyridin-4-yl-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one

HRID 988158Notes

Reaction equation

HRID 988158 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)=[CH:3][CH:2]=1.[NH:17]1[C:25]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[CH:19]=[C:18]1[CH:26]=O>>[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[C:9](=[CH:26][C:18]2[NH:17][C:25]4[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=4[CH:19]=2)[C:10](=[O:16])[NH:11]3)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 65020104,5,6,7-tetrahydro-1H-indole-2-carbaldehydeHCID 121115814-Pyridin-4-yl-1,3-dihydro-indol-2-one

Product 1

HCID 695839984-Pyridin-4-yl-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one

Procedure

4-Pyridin-4-yl-1,3-dihydroindol-2-one was condensed with 4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-cc8254f4bb9a44eb84dea943baa148db
Source dataset
uspto-grants-2003_10
Patent number
US06635640B2

Reaction notes

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