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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988171Generated: November 3, 2026

4-Pyridin-4-yl-1,3-dihydro-indol-2-one → 4-(2-Carboxyethyl)-3-methyl-5-(2-oxo-4-pyridin-4-yl-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid Ethyl Ester

https://huagongshe.com/reaction/988171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Pyridin-4-yl-1,3-dihydro-indol-2-oneHCID 12111581—
Reactant3-[5-(Ethoxycarbonyl)-2-formyl-4-methyl-1H-pyrrol-3-yl]propanoic acidHCID 15270623—
Product4-(2-Carboxyethyl)-3-methyl-5-(2-oxo-4-pyridin-4-yl-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid Ethyl EsterHCID 69584170—

Reaction Steps

4-Pyridin-4-yl-1,3-dihydroindol-2-one was condensed with 4-(2-carboxyethyl)-5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid ethyl ester to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635640B2
Source datasetuspto-grants-2003_10
ORD IDord-f87552659ec2470298d50ae30eeffd24
Source noteuspto-grants-2003_10