4-Pyridin-4-yl-1,3-dihydro-indol-2-one → 4-(4-Methoxyphenyl)-5-(2-oxo-4-pyridin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester

HRID 988173Notes

Reaction equation

HRID 988173 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)=[CH:3][CH:2]=1.[CH2:17]([O:19][C:20]([C:22]1[C:26]([C:27]2[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=2)=[C:25]([CH:35]=O)[NH:24][CH:23]=1)=[O:21])[CH3:18]>>[CH2:17]([O:19][C:20]([C:22]1[C:26]([C:27]2[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=2)=[C:25]([CH:35]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[C:4]3[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=3)[NH:11][C:10]2=[O:16])[NH:24][CH:23]=1)=[O:21])[CH3:18]

Participants

3

Reactant 2

HCID 121115814-Pyridin-4-yl-1,3-dihydro-indol-2-oneHCID 451126955-formyl-4-(4-methoxyphenyl)-1H-pyrrole-3-carboxylic acid ethyl ester

Product 1

HCID 695841184-(4-Methoxyphenyl)-5-(2-oxo-4-pyridin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester

Procedure

4-Pyridin-4-yl-1,3-dihydroindol-2-one was condensed with 5-formyl-4-(4-methoxyphenyl)-1H-pyrrole-3-carboxylic acid ethyl ester to give the title compound.

Sources & evidence

ORD record
ord-176a616359794bdeb7af9a4dbb187ede
Source dataset
uspto-grants-2003_10
Patent number
US06635640B2

Reaction notes

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