HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)indolin-2-one → HCID 67016610, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Reactant | 3-methyl-4-(piperidine-1-carbonyl)-1H-pyrrole-2-carbaldehyde | HCID 22135468 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67016610 | HCID 67016610 | 31.1% |
Reaction Steps
A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one (86.5 mg, 0.4 mmol) and 3-methyl-4-(piperidine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (88.1 mg, 0.4 mmol) in ethanol (2 mL) was stirred at room temperature for 4 days. The reaction was concentrated and the residue was column chromatographed to give 52 mg (31%) of the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-891b508ce3cd446682105ceb3fe32a5c |
| Source note | uspto-grants-2003_10 |