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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988174Generated: October 31, 2026

4-(Piperidin-4-yl)indolin-2-one → HCID 67016610, compound

https://huagongshe.com/reaction/988174

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Piperidin-4-yl)indolin-2-oneHCID 22135396—
Reactant3-methyl-4-(piperidine-1-carbonyl)-1H-pyrrole-2-carbaldehydeHCID 22135468—
SolventEthanolHCID 702—
ProductHCID 67016610HCID 6701661031.1%

Reaction Steps

A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one (86.5 mg, 0.4 mmol) and 3-methyl-4-(piperidine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (88.1 mg, 0.4 mmol) in ethanol (2 mL) was stirred at room temperature for 4 days. The reaction was concentrated and the residue was column chromatographed to give 52 mg (31%) of the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635640B2
Source datasetuspto-grants-2003_10
ORD IDord-891b508ce3cd446682105ceb3fe32a5c
Source noteuspto-grants-2003_10