HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)indolin-2-one → [2,4-Dimethyl-5-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]-acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Reactant | 2-(5-Formyl-2,4-dimethyl-1H-pyrrol-3-YL)acetic acid | HCID 22135418 | — |
| Product | [2,4-Dimethyl-5-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl]-acetic Acid | HCID 69584269 | — |
Reaction Steps
4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with (5-formyl-2,4-dimethyl-1H-pyrrol-3-yl)-acetic acid (40 mg, 0.23 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-256b63482f7e4b178f64412a33aeee6e |
| Source note | uspto-grants-2003_10 |