5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde → HCID 69584247, compound

HRID 988188Notes

Reaction equation

HRID 988188 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[N:17]1([CH2:23][CH2:24][O:25][C:26]2[CH:27]=[C:28]3[C:32](=[CH:33][CH:34]=2)[NH:31][C:30]([CH:35]=O)=[CH:29]3)[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[N:17]1([CH2:23][CH2:24][O:25][C:26]2[CH:27]=[C:28]3[C:32](=[CH:33][CH:34]=2)[NH:31][C:30]([CH:35]=[C:9]2[C:8]4[C:12](=[CH:13][CH:14]=[CH:15][C:7]=4[CH:4]4[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]4)[NH:11][C:10]2=[O:16])=[CH:29]3)[CH2:18][CH2:19][O:20][CH2:21][CH2:22]1

Participants

3

Reactant 2

HCID 220421095-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 221353964-(Piperidin-4-yl)indolin-2-one

Product 1

HCID 69584247HCID 69584247, compound

Procedure

4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with (5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde (60 mg, 0.23 mmol) to give the title compound.

Sources & evidence

ORD record
ord-644aa0347b6d437cb9b427407bfb844b
Source dataset
uspto-grants-2003_10
Patent number
US06635640B2

Reaction notes

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