HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)indolin-2-one → 3-[3-Methyl-5-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-piperidin-4-yl-1,3-dihydroindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Reactant | 3-methyl-5-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde | HCID 22135454 | — |
| Product | 3-[3-Methyl-5-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-piperidin-4-yl-1,3-dihydroindol-2-one | HCID 69584230 | — |
Reaction Steps
4-Piperidin-4-yl-1,3-dihydro-indol-2-one (45 mg, 0.2 mmol) was condensed with 3-methyl-5-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (52 mg, 0.23 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-6adda05daebb47d1bc8a43616d08c4de |
| Source note | uspto-grants-2003_10 |