5-Methyl-2-thiophenecarboxaldehyde → HCID 69584163, compound

HRID 988195Notes

Reaction equation

HRID 988195 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH3:17][C:18]1[S:22][C:21]([CH:23]=O)=[CH:20][CH:19]=1>>[CH3:23][C:21]1[S:22][C:18]([CH:17]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[CH:4]3[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]3)[NH:11][C:10]2=[O:16])=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 616635-Methyl-2-thiophenecarboxaldehydeHCID 221353964-(Piperidin-4-yl)indolin-2-one

Product 1

HCID 69584163HCID 69584163, compound

Procedure

4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 5-methylthiophene-2-carbaldehyde (28 mg, 0.23 mmol) to give the title compound.

Sources & evidence

ORD record
ord-8b380e0b12b6410e86b3c958f5206fcf
Source dataset
uspto-grants-2003_10
Patent number
US06635640B2

Reaction notes

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