HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)indolin-2-one → 4-(4-Methoxyphenyl)-5-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Reactant | 5-formyl-4-(4-methoxyphenyl)-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 45112695 | — |
| Product | 4-(4-Methoxyphenyl)-5-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester | HCID 69584229 | — |
Reaction Steps
4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 5-formyl-4-(4-methoxyphenyl)-1H-pyrrole-3-carboxylic acid ethyl ester (60 mg, 0.23 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-97cee65dd43f4654b5db5e077a9a1a22 |
| Source note | uspto-grants-2003_10 |