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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988206Generated: October 27, 2026

3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde → 3-[3,5-Dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-thiazol-2-yl-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/988206

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehydeHCID 12111582—
Reactant4-Thiazol-2-yl-1,3-dihydroindol-2-oneHCID 22135439—
Product3-[3,5-Dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-thiazol-2-yl-1,3-dihydroindol-2-oneHCID 24942409—

Reaction Steps

4-Thiazol-2-yl-1,3dihydro-indol-2-one (54 mg, 0.25 mmol) was condensed with 3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (69 mg, 0.275 mmol) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635640B2
Source datasetuspto-grants-2003_10
ORD IDord-b71bfb1e9da24c20adf125923b3726b3
Source noteuspto-grants-2003_10