HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyrimidin-5-yl-1,3-dihydroindol-2-one → 2-Methyl-4-[3-(4-methylpiperazin-1-yl)propyl]-5-(2-oxo-4-pyrimidin-5-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyrimidin-5-yl-1,3-dihydroindol-2-one | HCID 22135400 | — |
| Reactant | 5-formyl-2-methyl-4-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 58779587 | — |
| Product | 2-Methyl-4-[3-(4-methylpiperazin-1-yl)propyl]-5-(2-oxo-4-pyrimidin-5-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester | HCID 69584248 | — |
Reaction Steps
4-Pyrimidin-5-yl-1,3-dihydroindol-2-one (53 mg, 0.25 mmol) was condensed with 5-formyl-2-methyl-4-[3-(4-methylpiperazin-1-yl)-propyl]-1H-pyrrole-3-carboxylic acid ethyl ester (88 mg, 0.275 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-593381c1b6f4446f8c8f59c97ebc92b6 |
| Source note | uspto-grants-2003_10 |