HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde → 4-(6-Aminopyridin-3-yl)-3-[3,5-dimethyl-4-(4-methylpiperazin-1-ylcarbonyl)-1H-pyrrol-2-ylmethylene]-1,3-dihydroindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde | HCID 12111582 | — |
| Reactant | 4-(6-Aminopyridin-3-yl)-1,3-dihydroindol-2-one | HCID 22135432 | — |
| Product | 4-(6-Aminopyridin-3-yl)-3-[3,5-dimethyl-4-(4-methylpiperazin-1-ylcarbonyl)-1H-pyrrol-2-ylmethylene]-1,3-dihydroindol-2-one | HCID 69584125 | — |
Reaction Steps
4-(6-Aminopyridin-3-yl)-1,3-dihydroindol-2-one (56 mg, 0.25 mmol) was condensed with 3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (69 mg, 0.275 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-0fab66fe656344a59178c92e70a86be0 |
| Source note | uspto-grants-2003_10 |