Potassium Permanganate → HCID 70029514, compound

HRID 988225Notes

Reaction equation

HRID 988225 reaction equation
[Mn]([O-])(=O)(=O)=[O:2].[K+].[CH:7]([C:9]1[CH:10]=[CH:11][C:12]2[S:16][CH:15]=[C:14]([CH2:17][CH2:18][NH:19][C:20]([CH:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)=[O:21])[C:13]=2[CH:28]=1)=[O:8]>CC(C)=O.O.CC(C)=O>[CH:22]1([C:20]([NH:19][CH2:18][CH2:17][C:14]2[C:13]3[CH:28]=[C:9]([C:7]([OH:2])=[O:8])[CH:10]=[CH:11][C:12]=3[S:16][CH:15]=2)=[O:21])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

5

Reactant 2

HCID 516875Potassium PermanganateHCID 18007946HCID 18007946, compound

Product 1

HCID 70029514HCID 70029514, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

2.7 g of potassium permanganate in 50 ml of an acetone/water mixture (50/50) are added at room temperature to a solution of 6.88 mmol of the product obtained in Step E in 30 ml of acetone. The solution is stirred for 2 hours at room temperature and then filtered. The filtrate is concentrated under reduced pressure and chromatographed over silica gel to yield the title product.

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate is concentrated under reduced pressure
  3. customchromatographed over silica gel

Sources & evidence

ORD record
ord-3a8019740f6744ca902f382a5b2a6131
Source dataset
uspto-grants-2003_10
Patent number
US06635650B2

Reaction notes

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