3-(Quinolin-2-ylmethoxy)-propan-1-ol → HCID 18008077, compound

HRID 988264Notes

Reaction equation

HRID 988264 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][CH2:13][CH2:14][CH2:15][OH:16].Br[CH2:18][C:19]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:20]=1[O:21][CH2:22][C:23]#[N:24]>>[CH3:18][C:19]1[CH:28]=[CH:27][CH:26]=[C:25]([CH2:29][O:16][CH2:15][CH2:14][CH2:13][O:12][CH2:11][C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[N:1]=2)[C:20]=1[O:21][CH2:22][C:23]#[N:24]

Participants

3

Reactant 2

HCID 180080493-(Quinolin-2-ylmethoxy)-propan-1-olHCID 222414892-Cyanomethoxy-3-methylbenzyl bromide

Product 1

HCID 18008077HCID 18008077, compound

Procedure

MS (ESI) 377 (M+H)+. Prepared from 3-(quinolin-2-ylmethoxy)-propan-1-ol (EXAMPLE 34a) and (2-bromomethyl-6-methyl-phenoxy)-acetonitrile.

Sources & evidence

ORD record
ord-3805c392c9e74398bf13da702c9b15d5
Source dataset
uspto-grants-2003_10
Patent number
US06635655B1

Reaction notes

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