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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988531Generated: November 2, 2026

3-(Trifluoromethyl)benzeneacetic acid → 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/988531

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzeneacetic acidHCID 67695—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 15481772—

Reaction Steps

Following General Procedure BI above and using 3-trifluoromethyl-phenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635632B1
Source datasetuspto-grants-2003_10
ORD IDord-a68e6754c7bd4136a4c4b665cf6b144f
Source noteuspto-grants-2003_10