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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988540Generated: November 1, 2026

2-methylpropyl (2S)-2-aminopropanoate → N-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/988540

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
Reactant2-(3-Phenyl-1,2,4-thiadiazol-5-yl)acetic acidHCID 22492184—
ProductN-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl EsterHCID 22894976—

Reaction Steps

Following General Procedure BI above, and using (3-phenyl-1,2,4-thiadiazol-5-yl)acetic acid (CAS #90771-06-5) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635632B1
Source datasetuspto-grants-2003_10
ORD IDord-9c4e5d1cd4574ebd973c78b5c2182e9b
Source noteuspto-grants-2003_10