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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988635Generated: November 1, 2026

Triethylamine → HCID 21906421, compound

https://huagongshe.com/reaction/988635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant4-Chloronicotinic acidHCID 818229—
ReactantHCID 21906555HCID 21906555—
SolventEthanolHCID 702—
ProductHCID 21906421HCID 21906421—

Reaction Steps

Using a similar procedure to that described in Example 52, N-(5-chloropyridin-2-yl)-2-(piperidin-4-ylmethylamino)benzamide (100 mg, 0.29 mmol), 4-chloronicotinic acid (91 mg, 0.58 mmol), triethylamine (59 mg, 0.58 mmol), and ethanol (5 mL) yielded, after RPHPLC purification, 45 mg (33%) of the title compound as a trifluoroacetate salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635657B1
Source datasetuspto-grants-2003_10
ORD IDord-404faf5939ba4b0387241dabde0e5977
Source noteuspto-grants-2003_10