HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 21906421, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chloronicotinic acid | HCID 818229 | — |
| Reactant | HCID 21906555 | HCID 21906555 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21906421 | HCID 21906421 | — |
Reaction Steps
Using a similar procedure to that described in Example 52, N-(5-chloropyridin-2-yl)-2-(piperidin-4-ylmethylamino)benzamide (100 mg, 0.29 mmol), 4-chloronicotinic acid (91 mg, 0.58 mmol), triethylamine (59 mg, 0.58 mmol), and ethanol (5 mL) yielded, after RPHPLC purification, 45 mg (33%) of the title compound as a trifluoroacetate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635657B1 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-404faf5939ba4b0387241dabde0e5977 |
| Source note | uspto-grants-2003_10 |