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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988640Generated: October 30, 2026

Hydrochloric Acid → HCID 21906362, compound

https://huagongshe.com/reaction/988640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantCyclohexanoneHCID 7967—
ReactantSodium cyanoborohydrideHCID 5003444—
ReactantHCID 21906394HCID 21906394—
ProductHCID 21906362HCID 2190636265.2%

Reaction Steps

Using a similar procedure to that described in Example 9-C, N-(5-chloropyridin-2-yl)-2-[(piperidin-4-yloxycarbonyl)amino]benzamide (100 mg, 0.205 mmol), cyclohexanone (0.106 mL, 1.02 mmol), and sodium cyanoborohydride (51 mg, 0.82 mmol) yielded, after treatment with HCl, 33 mg (33%) of the title compound as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06635657B1
Source datasetuspto-grants-2003_10
ORD IDord-4d6754a5cb5742e6948ca21e66a12128
Source noteuspto-grants-2003_10