反应详情

To a stirring solution of dimethylamine (180 mL, 40% in water, 1.57 mol) in methanol (180 mL) at 0° C., was slowly added 4-nitrobenzenesulfonyl chloride (69.5 g, 314 mmol). After complete addition, the cold bath was removed; and, after stirring overnight, the mixture was filtered and the precipitate was washed with water and dried in vacuo to give 68 g (94%) of tan solid.

1. customat 0° C.
2. additionAfter complete addition
3. customthe cold bath was removed
4. filtrationthe mixture was filtered
5. washthe precipitate was washed with water
6. customdried in vacuo