HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-(Trifluoromethyl)phenyl)piperazine → 2,7-Bis-[3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-propionyl]-xanthene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-(Trifluoromethyl)phenyl)piperazine | HCID 4296 | — |
| Reactant | 2,7-Bis(3-chloropropionyl)xanthene | HCID 12340279 | — |
| Product | 2,7-Bis-[3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-propionyl]-xanthene | HCID 10283895 | — |
Reaction Steps
Prepared from compound 17 and 4-(3-trifluoromethyl-phenyl)-piperazine according to General Procedure C to give a solid. Mp 155-157° C. 1H NMR (CDCl3, 400 MHz) δ7.92-7.88 (m, 4H), 7.39 (t, J=8.8 Hz, 2H), 7.17-7.13 (m, 6H), 7.07 (dd, J=8.8, 2.0 Hz, 2H), 4.17 (s, 2H), 3.53-3.04 (m, 24H). Anal. (C41H40F6N4O3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635786B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-c57f3fd8dcf346529488ca947fbd7a0c |
| Source note | uspto-grants-2003_10 |