HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → methyl (2S)-2-amino-3-cyclohexylpropanoate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Cyclohexyl-L-alanine | HCID 712421 | — |
| Product | methyl (2S)-2-amino-3-cyclohexylpropanoate hydrochloride | HCID 22861687 | 83.9% |
Reaction Steps
This was synthesised according to Standard Procedure 1, using 3-cyclohexyl-L-alanine (3.0 g, 17.5 mmol), methanol (30 ml), and thionyl chloride (2.56 ml, 35 mmol). The product was isolated as a white solid (3.23 g, 83.9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06638919B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-d89c85505f1045d3961ffc1bf3b0720d |
| Source note | uspto-grants-2003_10 |