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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988983Generated: November 3, 2026

L-Alanine → p-Toluenesulfonic acid

https://huagongshe.com/reaction/988983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-AlanineHCID 5950—
ReactantCyclohexanolHCID 7966—
Reactantp-Toluenesulfonic acid monohydrateHCID 521998—
SolventTolueneHCID 1140—
Productp-Toluenesulfonic acidHCID 6101—

Reaction Steps

This was synthesised according to Standard Procedure 2, using L-Alanine (2.0 g, 22.5 mmol), cyclohexanol (2.34 ml, 22.5 mmol), p-toluene sulfonic acid monohydrate (4.7 g, 24.7 mmol), and toluene (100 ml). The p-toluene sulfonate salt was isolated as a pale orange solid (1.45 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06638919B2
Source datasetuspto-grants-2003_10
ORD IDord-bcbc99c232284a1caa59a3933534ddee
Source noteuspto-grants-2003_10