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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 988988Generated: October 25, 2026

Cyclohexanecarboxaldehyde → (2-Cyclohexyl-imidazo[1,2-a]pyrazin-3-yl)-(6-isocyano-hexyl)-amine

https://huagongshe.com/reaction/988988

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarboxaldehydeHCID 16275—
ReactantAminopyrazineHCID 78747—
Reactant1,6-DiisocyanohexaneHCID 3391105—
SolventPerchloric AcidHCID 24247—
Product(2-Cyclohexyl-imidazo[1,2-a]pyrazin-3-yl)-(6-isocyano-hexyl)-amineHCID 9883789—

Reaction Steps

Compound (3) was prepared in accordance with general instructions 1 from 1.0 ml aminopyrazine solution (0.1 M, MC), 0.575 ml 1,6-diisocyanohexane solution (0.2 M, MC), 0.500 ml cyclohexanecarbaldehyde solution (0.3 M, MC), and 10 μl perchloric acid (w=20%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06638933B2
Source datasetuspto-grants-2003_10
ORD IDord-39fcd23a72df4c698000feee9e7929d3
Source noteuspto-grants-2003_10