3,4,5-Trimethoxybenzaldehyde → HCID 18004777, compound

HRID 989006Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:8][C:9]([N+:16]#[C-:17])([CH3:15])[CH2:10][C:11]([CH3:14])([CH3:13])[CH3:12].[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:25]=[C:26]([O:30][CH3:31])[C:27]=1[O:28][CH3:29])[CH:23]=O>>[CH3:8][C:9]([NH:16][C:17]1[N:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]2=[N:1][C:23]=1[C:22]1[CH:25]=[C:26]([O:30][CH3:31])[C:27]([O:28][CH3:29])=[C:20]([O:19][CH3:18])[CH:21]=1)([CH3:15])[CH2:10][C:11]([CH3:14])([CH3:13])[CH3:12]

Participants

Reactant 3

HCID 68583,4,5-Trimethoxybenzaldehyde

HCID 104392-Aminopyridine

HCID 267251,1,3,3-Tetramethylbutyl isocyanide

Product 1

HCID 18004777HCID 18004777, compound

Procedure

Compound (33) was prepared in accordance with general instructions 1 from 1.0 ml 2-aminopyridine solution (0.1 M, MC), 0.575 ml 1,1,3,3-tetramethylbutyl isocyanide solution (0.2 M, MC), 0.500 ml 3,4,5-trimethoxybenzaldehyde solution (0.3 M, MC), and 10 Al perchloric acid (w=20%).

Sources & evidence

ORD record: ord-6a6301d9c4d340d78040733fe722960c
Source dataset: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06638933B2

Reaction notes

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