反应详情

A mixture of 2-bromo-3′-nitroacetophenone (5 g, 20 mmol) and thionicotinamide (2.76 g, 20 mmol) in ethanol (25 ml) was heated to reflux for 1 h, during which time extensive precipitation occurred. Filtration and drying afforded the product as a yellow solid (6.7 g, 92%).

1. temperaturewas heated
2. temperatureto reflux for 1 h, during which time extensive precipitation
3. filtrationFiltration
4. customdrying