Ammonium Hydroxide → HCID 59088101, compound

Participants

Reaction Steps

A solution of 7-(benzyloxy)-2-[2-methoxyethenyl]-chroman (1.0 g, 3.3 mmol) in THF is treated with perchloric acid (0.3 ml), stirred at room temperature for 15 minutes, poured into dilute NH4OH and extracted with ether. The combined extracts are dried over MgSO4 and concentrated in vacuo. The resultant residue is chromatographed (silica gel/20% EtOAc in hexanes as eluent) to give the title product as a colorless oil, 0.484 g (50% yield), identified by NMR and mass spectral analyses.

Provenance & Evidence