HCID 22137846, compound → HCID 18005856, compound

Participants

Reaction Steps

A solution of 6-(benzyloxy)benzofuran-2-carboxylic acid (3.4 g, 12.6 mmol) in aqueous NaOH (2.5N, 40 mL) is treated with 6% Na—Hg (20 g), stirred for 16 hr, allowed to stand without stirring and decanted. The supernatant is acidified with HCl and filtered. The filtercake is air-dried to afford the title product as a white solid, 2.2 g (64% yield) mp 118-119° C., identified by NMR and mass spectral analyses.

Provenance & Evidence