4-(N-piperidinomethylcarbonyl-N-methyl-amino)-nitrobenzene → 4-(N-piperidinomethylcarbonyl-N-methyl-amino)-aniline

HRID 989403Notes

Reaction equation

HRID 989403 reaction equation
[N:1]1([CH2:7][C:8]([N:10]([C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=2)[CH3:11])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>CO.[Pd]>[N:1]1([CH2:7][C:8]([N:10]([C:12]2[CH:13]=[CH:14][C:15]([NH2:18])=[CH:16][CH:17]=2)[CH3:11])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 235071034-(N-piperidinomethylcarbonyl-N-methyl-amino)-nitrobenzene

Product 1

HCID 225696444-(N-piperidinomethylcarbonyl-N-methyl-amino)-aniline

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Prepared analogously to Example Id by catalytic hydrogenation of 4-(N-piperidinomethylcarbonyl-N-methyl-amino)-nitrobenzene in methanol over palladium/charcoal.

Sources & evidence

ORD record
ord-8e49c791927f421088ff3eb081453b1e
Source dataset
uspto-grants-2003_10
Patent number
US06638965B2

Reaction notes

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