Hydrogen Peroxide → Bis[1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-yl] Succinate

HRID 989531Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 989531
OO.[OH:3][N:4]1[C:9]([CH3:11])([CH3:10])[CH2:8][CH:7]([O:12][C:13](=[O:30])[CH2:14][CH2:15][C:16]([O:18][CH:19]2[CH2:24][C:23]([CH3:26])([CH3:25])[N:22]([OH:27])[C:21]([CH3:29])([CH3:28])[CH2:20]2)=[O:17])[CH2:6][C:5]1([CH3:32])[CH3:31].S([O-])([O-])=O.[Na+].[Na+].[C:39]([OH:43])([CH3:42])([CH3:41])[CH3:40]>>[OH:43][C:39]([CH3:42])([CH3:41])[CH2:40][O:27][N:22]1[C:21]([CH3:29])([CH3:28])[CH2:20][CH:19]([O:18][C:16](=[O:17])[CH2:15][CH2:14][C:13]([O:12][CH:7]2[CH2:6][C:5]([CH3:32])([CH3:31])[N:4]([O:3][CH2:40][C:39]([OH:43])([CH3:42])[CH3:41])[C:9]([CH3:11])([CH3:10])[CH2:8]2)=[O:30])[CH2:24][C:23]1([CH3:26])[CH3:25]

Komponenten

5

Edukt 4

HCID 784Hydrogen PeroxideHCID 6386tert-ButanolHCID 24437Sodium SulfiteHCID 326921Bis(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) butanedioate

Produkt 1

HCID 54162330Bis[1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-yl] Succinate

Versuchsvorschrift

Aqueous hydrogen peroxide is-added to a mixture of bis(1-oxyl-2,2,6,6-tetramethylpieridin-4-yl)succinate and ferrous chloride tetrahydrate in tert-butyl alcohol at 30-50° C. Excess peroxide is decomposed with aqeuous sodium sulfite solution. The organic layer is concentrated and the crude product is purified by flash chromatography on silica gel to afford the title compound.

Aufarbeitung

  1. concentrationThe organic layer is concentrated
  2. customthe crude product is purified by flash chromatography on silica gel

Quellen und Nachweise

ORD-Eintrag
ord-7511a2eb926a4072b9bd1e670852831a
Quelldatensatz
uspto-grants-2003_10
Patentnummer
US06638997B2

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