反应详情

In 3.0 l of toluene was dissolved 300 g (930 mmol) of the 2-(2-(trans-4-(trans-4-propylcyclohexyl)cyclohexyl)ethyl)-1,3-dioxane obtained by the procedures described above, 428 g (9300 mmol) of formic acid was added thereto, and they were heated to reflux for 4 hours. The reaction mixture was washed with 600 ml of saturated aqueous sodium bicarbonate solution twice and with 1.0 l of water five times, and the solvent was distilled off under a reduced pressure to obtain 240 g of a crude 3-(trans-4-(trans-4-propylcyclohexyl)-cyclohexyl)propanal.

1. customobtained by the procedures
2. additionwas added
3. temperaturethey were heated
4. temperatureto reflux for 4 hours
5. washThe reaction mixture was washed with 600 ml of saturated aqueous sodium bicarbonate solution twice
6. distillationwith 1.0 l of water five times, and the solvent was distilled off under a reduced pressure