Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 2-(Bromomethyl)-6-fluoronaphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-Fluoro-6-methylnaphthalene | HCID 2727845 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 2-(Bromomethyl)-6-fluoronaphthalene | HCID 594633 | — |
반응 단계
6-Fluoro-2-methylnaphthalene (20.5 g, 128 mmol, prepared by adaptation of the method of Wolinska-Mocydlarz et al2) and NBS (22.8 g, 128 mmol) were heated at reflux for 16 hr in CCl4 (210 mL) during which time, benzoyl peroxide (2.5 g) was added portionwise. The cooled solution was filtered and evaporated and the residue was extracted thoroughly with hexane (4×250 mL). The extracts were decanted from tarry material, combined and evaporated to give the product as a yellow solid, 29.8 g (97%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06458779B1 |
| 출처 데이터셋 | uspto-grants-2002_10 |
| ORD ID | ord-5cd8038720464ff5a4fabe12d3de951b |
| 출처 메모 | uspto-grants-2002_10 |