1-methyl-1H-pyrazole-4-sulfonyl chloride → HCID 70158797, compound

HRID 989686Notes

Reaction equation

HRID 989686 reaction equation
Cl.[C:2]([C:4]1[CH:5]=[CH:6][C:7]2[N:13](CC3C=NC=CC=3)[CH2:12][C@@H:11]([CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[N:10]([S:28](C3SC=CC=3)(=[O:30])=[O:29])[CH2:9][C:8]=2[CH:36]=1)#[N:3].[CH3:37][N:38]1[CH:42]=[C:41](S(Cl)(=O)=O)[CH:40]=[N:39]1>>[CH3:37][N:38]1[CH:42]=[C:41]([S:28]([N:10]2[CH2:9][C:8]3[CH:36]=[C:4]([C:2]#[N:3])[CH:5]=[CH:6][C:7]=3[NH:13][CH2:12][C@H:11]2[CH2:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)(=[O:29])=[O:30])[CH:40]=[N:39]1

Participants

3

Reactant 2

HCID 170247301-methyl-1H-pyrazole-4-sulfonyl chlorideHCID 131723534HCID 131723534, compound2×

Product 1

HCID 70158797HCID 70158797, compound

Procedure

The title compound was prepared from Compound A of Example 23 and 1-methyl-1H-pyrazole-4-sulfonyl chloride following the procedure of Compound B of Example 23.

Sources & evidence

ORD record
ord-544b182ad9f4427abedf3f87b2afe85c
Source dataset
uspto-grants-2002_10
Patent number
US06458783B1

Reaction notes

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