4-Methoxybenzenesulfonyl chloride → HCID 15522662, compound
Reaction equation
Cl.[C:2]([C:4]1[CH:5]=[CH:6][C:7]2[N:13](CC3C=NC=CC=3)[CH2:12][C@@H:11]([CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[N:10]([S:28]([C:31]3SC=C[CH:35]=3)(=[O:30])=[O:29])[CH2:9][C:8]=2[CH:36]=1)#[N:3].[CH3:37][O:38][C:39]1[CH:44]=CC(S(Cl)(=O)=O)=[CH:41][CH:40]=1>>[CH3:37][O:38][C:39]1[CH:44]=[CH:35][C:31]([S:28]([N:10]2[CH2:9][C:8]3[CH:36]=[C:4]([C:2]#[N:3])[CH:5]=[CH:6][C:7]=3[NH:13][CH2:12][C@H:11]2[CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)(=[O:29])=[O:30])=[CH:41][CH:40]=1Participants
3
Procedure
The title compound was prepared from Compound A of Example 23 and 4-methoxyphenylsulfonyl chloride following the procedure of Compound B of Example 23.
Sources & evidence
- ORD record
- ord-7a6a48c169734e52a7a97000c5fea813
- Source dataset
- uspto-grants-2002_10
- Patent number
- US06458783B1
Reaction notes
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