HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbonic acid-guanidine (1:1) → HCID 178433375, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbonic acid-guanidine (1:1) | HCID 286947 | — |
| Reactant | Ethyl 2-(2-cyanoethyl)-3-oxobutanoate | HCID 13328085 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 178433375 | HCID 178433375 | 64.5% |
Reaction Steps
A mixture of ethyl 2-(2-cyanoethyl)-3-oxobutanoate (9 g, 49 mmol), guanidine carbonate (5.30 g, 29.4 mmol) and pyridine (49 ml) was kept at 100° C. for 8 hours. The procedure according to pro-treatment of Reference-example 6 was carried out to give the object compound (3.38 g, 38.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458798B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-e4c5fef0109e4f689c2bb48abb33f746 |
| Source note | uspto-grants-2002_10 |