反应详情

A mixture of 2,4-dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine (410 mg) and pentylamine (1 ml) were stirred at room temperature for 8 hours. The reaction mixture was poured into an aqueous ammonium chloride solution and the solution was extracted with chloroform. The organic layer was washed with saturated brine, dried over sodium sulfate and concentrated in vacuo to give the object compound (296 mg, 65%).

1. extractionthe solution was extracted with chloroform
2. washThe organic layer was washed with saturated brine
3. dry with materialdried over sodium sulfate
4. concentrationconcentrated in vacuo