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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 989734Generated: October 25, 2026

Methyl 2-(4-bromophenyl)acetate → 5-(4-Bromo-benzyl)-3-(1-methyl-4-phenyl-butyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one

https://huagongshe.com/reaction/989734

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(4-bromophenyl)acetateHCID 316783—
Reactant5-Amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamideHCID 11149992—
Product5-(4-Bromo-benzyl)-3-(1-methyl-4-phenyl-butyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-oneHCID 135487673—

Reaction Steps

Analogously to the procedure of Example 1, the title compound is prepared from 1.0 g (3.8 mmol) of 5-amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamide and 2.61 g (11.4 mmol) of methyl 4-bromophenylacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06458796B1
Source datasetuspto-grants-2002_10
ORD IDord-f0003b5f6e4d4d1eaaa5a6cd718e2e1e
Source noteuspto-grants-2002_10