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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 989736Generated: October 25, 2026

Methyl 4-chlorophenylacetate → 5-(4-Chloro-benzyl)-3-(1-methyl-4-phenyl-butyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one

https://huagongshe.com/reaction/989736

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-chlorophenylacetateHCID 104196—
Reactant5-Amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamideHCID 11149992—
Product5-(4-Chloro-benzyl)-3-(1-methyl-4-phenyl-butyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-oneHCID 135528860—

Reaction Steps

Analogously to the procedure of Example 5, the title compound is prepared from 1.0 g (3.8 mmol) of 5-amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamide and 1.83 g (10.7 mmol) of methyl 4-chlorophenylacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06458796B1
Source datasetuspto-grants-2002_10
ORD IDord-39bb2fd8f54246bba4901c7b1fb782c8
Source noteuspto-grants-2002_10