5-Amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamide → HCID 135423083, compound

HRID 989742Notes

Reaction equation

HRID 989742 reaction equation
[NH2:1][C:2]1[N:6]([CH:7]([CH3:17])[CH2:8][CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:5]=[N:4][C:3]=1[C:18]([NH2:20])=[O:19].[CH3:21][N:22]([CH3:34])[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30](OC)=O)=[CH:25][CH:24]=1>>[CH3:34][N:22]([CH3:21])[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30]2[NH:20][C:18](=[O:19])[C:3]3[N:4]=[N:5][N:6]([CH:7]([CH3:17])[CH2:8][CH2:9][CH2:10][C:11]4[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=4)[C:2]=3[N:1]=2)=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 111499925-Amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamideHCID 15571460HCID 15571460, compound

Product 1

HCID 135423083HCID 135423083, compound

Procedure

Analogously to the procedure of Example 5, the title compound is prepared from 1.0 g (3.8 mmol) of 5-amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamide and 1.77 g (9.15 mmol) of methyl 4-dimethylaminophenylacetate.

Sources & evidence

ORD record
ord-a785762e601d4c349a10456e18825a33
Source dataset
uspto-grants-2002_10
Patent number
US06458796B1

Reaction notes

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