Methyl 2-(1,3-dioxaindan-5-yl)acetate → HCID 135544080, compound
Reaction equation
[NH2:1][C:2]1[N:6]([CH:7]([CH3:17])[CH2:8][CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:5]=[N:4][C:3]=1[C:18]([NH2:20])=[O:19].[CH2:21]1[O:29][C:28]2[CH:27]=[CH:26][C:25]([CH2:30][C:31](OC)=O)=[CH:24][C:23]=2[O:22]1>>[O:29]1[C:28]2[CH:27]=[CH:26][C:25]([CH2:30][C:31]3[NH:20][C:18](=[O:19])[C:3]4[N:4]=[N:5][N:6]([CH:7]([CH3:17])[CH2:8][CH2:9][CH2:10][C:11]5[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=5)[C:2]=4[N:1]=3)=[CH:24][C:23]=2[O:22][CH2:21]1Participants
3
Procedure
Analogously to the procedure of Example 5, the title compound is prepared from 18 mg (0.066 mmol) of 5-amino-1-(1-methyl-4-phenyl-butyl)-1H-[1,2,3]triazole-4-carboxamide and 40.8 g (0.21 mmol) of methyl 3,4-methylenedioxyphenylacetate.
Sources & evidence
- ORD record
- ord-a76464488a244d0fad4ea403c5f7d2e4
- Source dataset
- uspto-grants-2002_10
- Patent number
- US06458796B1
Reaction notes
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