Methyl 2-(1,3-dioxaindan-5-yl)acetate → HCID 135515578, compound

HRID 989745Notes

Reaction equation

HRID 989745 reaction equation
[NH2:1][C:2]1[N:6]([CH:7]([CH:17]([OH:19])[CH3:18])[CH2:8][CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:5]=[N:4][C:3]=1[C:20]([NH2:22])=[O:21].[CH2:23]1[O:31][C:30]2[CH:29]=[CH:28][C:27]([CH2:32][C:33](OC)=O)=[CH:26][C:25]=2[O:24]1>>[O:31]1[C:30]2[CH:29]=[CH:28][C:27]([CH2:32][C:33]3[NH:22][C:20](=[O:21])[C:3]4[N:4]=[N:5][N:6]([CH:7]([CH:17]([OH:19])[CH3:18])[CH2:8][CH2:9][CH2:10][C:11]5[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=5)[C:2]=4[N:1]=3)=[CH:26][C:25]=2[O:24][CH2:23]1

Participants

3

Reactant 2

HCID 266588Methyl 2-(1,3-dioxaindan-5-yl)acetateHCID 18419355HCID 18419355, compound

Product 1

HCID 135515578HCID 135515578, compound

Procedure

Analogously to the procedure of Example 29, the title compound is prepared from 10 mg (0.024 mmol) of 5-amino-1-[1-(1-hydroxy-ethyl)-4-phenyl-butyl]-1H-[1,2,3]triazole-4-carboxamide and 20 mg (0.107 mmol) of methyl 3,4-methylenedioxyphenylacetate.

Sources & evidence

ORD record
ord-8f19e5d5ea84485db5804e08cf4fc0ec
Source dataset
uspto-grants-2002_10
Patent number
US06458796B1

Reaction notes

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