HCID 559409, compound → HCID 135430986, compound

HRID 989748Notes

Reaction equation

HRID 989748 reaction equation
[NH2:1][C:2]1[N:6]([CH:7]([CH:17]([OH:19])[CH3:18])[CH2:8][CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:5]=[N:4][C:3]=1[C:20]([NH2:22])=[O:21].[O:23]1[CH2:28][CH2:27][N:26]([S:29]([C:32]2[CH:37]=[CH:36][C:35]([CH2:38][C:39](OC)=O)=[CH:34][CH:33]=2)(=[O:31])=[O:30])[CH2:25][CH2:24]1>>[OH:19][CH:17]([CH:7]([N:6]1[C:2]2[N:1]=[C:39]([CH2:38][C:35]3[CH:34]=[CH:33][C:32]([S:29]([N:26]4[CH2:27][CH2:28][O:23][CH2:24][CH2:25]4)(=[O:31])=[O:30])=[CH:37][CH:36]=3)[NH:22][C:20](=[O:21])[C:3]=2[N:4]=[N:5]1)[CH2:8][CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[CH3:18]

Participants

3

Reactant 2

HCID 559409HCID 559409, compoundHCID 18419355HCID 18419355, compound

Product 1

HCID 135430986HCID 135430986, compound

Procedure

Analogously to the procedure of Example 29, the title compound is prepared from 10 mg (0.024 mmol) of 5-amino-1-[1-(1-hydroxy-ethyl)-4-phenyl-butyl]-1H-[1,2,3]triazole-4-carboxamide and 30 mg (0.107 mmol) of methyl 4-morpholinosulphonylphenylacetate.

Sources & evidence

ORD record
ord-ecebcf224e5d4f498f906fd57f0952ec
Source dataset
uspto-grants-2002_10
Patent number
US06458796B1

Reaction notes

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