HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzoic Acid → Benzoic acid, 4-hydroxy-, (4-methoxyphenyl)methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzoic Acid | HCID 135 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Methyloxybenzyl chloride | HCID 69993 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Benzoic acid, 4-hydroxy-, (4-methoxyphenyl)methyl ester | HCID 12119266 | — |
Reaction Steps
4-Hydroxybenzoic acid (1.38 g) was esterified by alkylation with 4-methoxybenzyl chloride by the method described in Example A-I-1, step a. The title compound (2.06 g) was obtained after silica gel column chromatography (0, 1, 2, 3% ethanol in dichloromethane). Rf (2%MeOH/CHCl3) 0.40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458772B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-7838a1ddf9884705bf9db20d2aa13cba |
| Source note | uspto-grants-2002_10 |