HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 4-Methoxybenzyl 4(N-benzyloxycarbonyl-L-valyloxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | N-Carbobenzoxy-L-valine | HCID 726987 | — |
| Reactant | Benzoic acid, 4-hydroxy-, (4-methoxyphenyl)methyl ester | HCID 12119266 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Methoxybenzyl 4(N-benzyloxycarbonyl-L-valyloxy)benzoate | HCID 23387546 | — |
Reaction Steps
4-Methoxybenzyl 4hydroxybenzoate was acylated with N-benzyloxycarbonyl-L-valine by the method described in Example A-I-1, step b. The title compound (2.71 g) was obtained after silica gel column chromatography (0, 1% ethanol in dichloromethane). Rf (2%MeOH/CHCl3) 0.70.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458772B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-7bbb0634c8804c038a51f2157a89cb1d |
| Source note | uspto-grants-2002_10 |