HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Chloromethyl 4-(N-benzyloxycarbonyl-L-valyloxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 4-(N-benzyloxycarbonyl-L-valyloxy)benzoic acid | HCID 54468851 | — |
| Product | Chloromethyl 4-(N-benzyloxycarbonyl-L-valyloxy)benzoate | HCID 54343725 | — |
Reaction Steps
4-(N-benzyloxycarbonyl-L-valyloxy)benzoic acid was esterified by the method described in Example A-I-1, step d. The title compound (0.95 g) was obtained after silica gel column chromatography (0, 1% ethanol in dichloromethane). Rf (2%MeOH/CHCl3) 0.80.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458772B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-9582c4464caa4cf88dcfe9f9cb22f057 |
| Source note | uspto-grants-2002_10 |