2-Dimethylaminopyridine → HCID 23387542, compound

Participants

Reaction Steps

4-Methoxybenzyl 2-hydroxyphenylacetate 3 g, 11 mmol), N,N,-dicyclohexyl-carbodiimide (2.7 g, 13.2 mmol), dimethylaminopyridine (0.134 g, 1.1 mmol) and CBz-L-valine (3.3 g, 13.2 mmol) were dissolved in dichloromethane (50 ml). After the weekend the solid was filtered off, the solvent removed under reduced pressure and the crude product purified by chromatography (ethyl acetate, hexane, 1:2) to give the title compound (5.2 g, 93%).

Provenance & Evidence