HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyceraldehyde → Benzyl 4,5-dihydroxy-2-pentenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyceraldehyde | HCID 751 | — |
| Reactant | (Benzyloxycarbonylmethyl)triphenylphosphonium bromide | HCID 11214019 | — |
| Solvent | 1,2-Epoxybutane | HCID 7834 | — |
| Product | Benzyl 4,5-dihydroxy-2-pentenoate | HCID 54529065 | — |
Reaction Steps
A mixture of DL-glycerinaldehyde (4.5 g, 50 mmole) and (benzyloxycarbonylmethyl)-triphenyl-phosphoniumbromide (24.57 g, 50 mmole) in 100 ml 1,2-epoxybutane was refluxed overnight. The mixture was evaporated under vacuum and the product was isolated by silica gel column chromatography. Yield: 8 g=71%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458772B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-bf93b888e5ab4bcd9be5e6dda82bab73 |
| Source note | uspto-grants-2002_10 |