HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-methylisoxazol-5-amine → HCID 23445315, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Reactant | HCID 23445331 | HCID 23445331 | — |
| Product | HCID 23445315 | HCID 23445315 | 33% |
Reaction Steps
N-(4-Bromo-3-methyl-5-isoxazolyl)-2-[trans-3,4-(methylenedioxy)-cinnamyl]thiophene-3-sulfonamide was prepared in the same manner as described in Example 9 by reaction of 3-chlorosulfonyl-2-[trans-3,4-(methylenedioxy)cinnamyl]thiophene with 5-amino-4-bromo-3-methylisoxazole. The crude product was purified by HPLC resulting in a 33% yield, m.p. 147-149° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458805B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-71a8fe8dc5c24f9391ef036b54714fb4 |
| Source note | uspto-grants-2002_10 |