4-Bromoaniline → HCID 6481531, compound

HRID 990106Notes

Reaction equation

[Cl:1][C:2]1[CH:13]=[C:6]2[C:7]([O:9]C(=O)[NH:11][C:5]2=[CH:4][CH:3]=1)=O.[Br:14][C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1>>[Br:14][C:15]1[CH:21]=[CH:20][C:18]([NH:19][C:7](=[O:9])[C:6]2[CH:13]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[NH2:11])=[CH:17][CH:16]=1

Participants

Reactant 2

HCID 78074-Bromoaniline

HCID 784805-Chloroisatoic anhydride

Product 1

HCID 6481531HCID 6481531, compound

Procedure

A similar procedure starting from 5-chloroisatoic anhydride and 4-bromoaniline gave N-(4-bromophenyl)-2-amino-5-chlorobenzamide which gave the expected NMR, MS, and elemental analysis.

Sources & evidence

ORD record: ord-ad38d840f48a407ea14b848da56c71fd
Source dataset: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06458845B1

Reaction notes

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