[2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-(2-methyl-5-{1-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-1H-[1,2,3]triazol-4-yl}-phenyl)-methanone → HCID 11541444, compound

HRID 99013Notes

Reaction equation

HRID 99013 reaction equation
[Cl:1][c:2]1[c:3]([C:17](=[O:18])[c:19]2[c:20]([CH3:39])[cH:21][cH:22][c:23](-[c:25]3[n:26][n:27][n:28]([CH2:30][CH2:31][O:32][CH:33]4[O:34][CH2:35][CH2:36][CH2:37][CH2:38]4)[cH:29]3)[cH:24]2)[cH:4][cH:5][c:6]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:7]1.[Cl:40][c:41]1[cH:42][c:43]([NH:44][c:45]2[cH:46][cH:47][c:48]([F:49])[cH:50][c:51]2[F:52])[cH:53][cH:54][c:55]1[C:56](=[O:57])[c:58]1[cH:59][c:60]([C:61]#[CH:62])[cH:63][cH:64][c:65]1[O:66][CH3:67].[N:68]([CH2:69][CH2:70][O:71][CH:72]1[CH2:73][CH2:74][CH2:75][CH2:76][O:77]1)=[N+:78]=[N-:79]>>[Cl:1][c:2]1[c:3]([C:17](=[O:18])[c:19]2[c:20]([O:57][CH3:56])[cH:21][cH:22][c:23](-[c:25]3[n:26][n:27][n:28]([CH2:30][CH2:31][O:32][CH:33]4[O:34][CH2:35][CH2:36][CH2:37][CH2:38]4)[cH:29]3)[cH:24]2)[cH:4][cH:5][c:6]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:7]1

Participants

4

Reactant 3

HCID 11706669[2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-(2-methyl-5-{1-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-1H-[1,2,3]triazol-4-yl}-phenyl)-methanoneHCID 600742872-(2-Azidoethoxy)oxaneHCID 86605526[2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-(5-ethynyl-2-methoxy-phenyl)-methanone

Product 1

HCID 11541444HCID 11541444, compound

Sources & evidence

ORD record
ord-f1f431a7cf98457eb93da3a0d7daa89d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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