1287-16-7 → 1273-90-1

HRID 990162Notes

Reaction equation

HRID 990162 reaction equation
[C-:1]1([CH2:6][C:7](O)=[O:8])[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-:10]1[CH:14]=[CH:13][CH:12]=[CH:11]1.[Fe+2:15].[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC>[C-:1]1([CH2:6][CH2:7][OH:8])[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-:10]1[CH:14]=[CH:13][CH:12]=[CH:11]1.[Fe+2:15]

Participants

4

Reactant 2

HCID 157685011287-16-7HCID 21226445Aluminium lithium hydride2×

Product 1

HCID 158548031273-90-1

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

2-ferrocenylethyl alcohol was synthesized by reducing ferrocenyl acetic acid with lithiumaluminum hydride. 1.4 g of LiAlH4 are placed in a flask containing ether and equipped with a soxhlet apparatus. Ferrocene acetic acid (0.9 g) is extracted by this apparatus for 48 hours. After cooling, the excess reagent is decomposed with water and the solution washed thoroughly with a solution of sodium bicarbonate, dried and evaporated to dryness. The residual oil is crystallized from hexane. It has a melting point of 41° C.

Workup

  1. customequipped with a soxhlet apparatus
  2. extractionFerrocene acetic acid (0.9 g) is extracted by this apparatus for 48 hours
  3. temperatureAfter cooling
  4. washthe solution washed thoroughly with a solution of sodium bicarbonate
  5. customdried
  6. customevaporated to dryness
  7. customThe residual oil is crystallized from hexane

Sources & evidence

ORD record
ord-11fee72ee420428a92ac82d01549948c
Source dataset
uspto-grants-2002_10
Patent number
US06458907B1

Reaction notes

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